10 Best Cold Sore Creams 2025 in the United States

This red light therapy device is designed to alleviate cold sores and various other conditions such as muscle stiffness, joint pain, and inflammation. It is multifunctional, featuring a detachable tip for both facial and body applications, making it versatile for treating cold sores on the lips as well as pain relief across different body parts.

The device operates using enhanced wavelengths of red and infrared light, which are known to aid in healing and pain relief. However, users should note that some wavelengths are not visible to the naked eye, which might cause concern if the device appears inactive. The device's exclusive pulse mode is beneficial for sensitive skin, preventing overheating during use.

Its simplicity in design, with a five-minute timer and single-button operation, makes it user-friendly for all ages. The inclusion of two rechargeable batteries and USB Type C compatibility ensures it is travel-ready. Potential buyers should be aware that this is not a traditional cream but a light therapy device, which might not fit everyone's preferences or needs.

Abreva 10 Percent Docosanol Cold Sore Treatment is a popular choice for those dealing with fever blisters, effectively helping to shorten the healing time. Containing 10 percent docosanol, it's clinically proven to address the symptoms associated with cold sores, such as tingling, pain, burning, and itching, and can help heal them in as little as 2.5 days. This makes it a strong contender in the cold sore cream category, especially for people seeking quick relief and recovery.

The product comes in two 0.07 oz tubes, which are portable and easy to carry around. This convenience makes it suitable for individuals who may experience sudden outbreaks and need treatment on the go. Being the number one dermatologist-recommended cold sore treatment also adds to its credibility, making users feel more confident in its effectiveness.

Abreva cold sore cream is well-suited for individuals looking for an effective, fast-acting solution to cold sores, particularly for those who appreciate convenience and dermatologist backing. Potential users should be mindful of the need for regular application to achieve the best outcomes.

The Mederma Fever Blister Discreet Healing Patch is designed to offer an effective solution for those dealing with cold sores. One of its standout features is its ability to instantly conceal cold sores, allowing users to feel more confident in social situations. The patches utilize hydrocolloid gel technology, which not only hides the sore but also creates an environment conducive to faster healing. Each patch can provide protection for up to 12 hours, helping to safeguard the sore from further contamination and irritation, which is particularly beneficial during the early stages of a cold sore outbreak.

In terms of ease of use, these patches come with a no-touch applicator, making it simple to apply them accurately without the risk of spreading the virus. They are also designed to stay in place, providing both protection and concealment.

The Mederma Fever Blister Discreet Healing Patch is a solid choice for anyone looking to manage the appearance of cold sores while promoting healing. It particularly benefits those who prioritize discretion and ease of use in their treatment options.